Chiral discrimination of amlodipine from pharmaceutical products using capillary electrophoresis
نویسندگان
چکیده
منابع مشابه
Chiral ionic liquids for enantioseparation of pharmaceutical products by capillary electrophoresis.
A chiral ionic liquid (IL), S-[3-(chloro-2-hydroxypropyl)trimethylammonium] [bis((trifluoromethyl)sulfonyl)amide] (S-[CHTA](+)[Tf(2)N](-)), which can be easily and readily synthesized in a one-step process from commercially available reagents, can be successfully used both as co-electrolyte and as a chiral selector for CE. A variety of pharmaceutical products including atenolol, propranolol, wa...
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Due to high resolution power of sulfated cyclodextrins (HS-CDs), utilization of these selectors for chiral resolution of 7 basic and 2 zwitterionic drugs have been examined. Experiments were performed on a HP3DCE instrument equipped with an on-column diode array UV absorbance detector. Fused silica capillaries with an inner diameter of 50 ?m, an outer diameter of 365 ?m, and a total length of 4...
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Due to high resolution power of sulfated cyclodextrins (HS-CDs), utilization of these selectors for chiral resolution of 7 basic and 2 zwitterionic drugs have been examined. Experiments were performed on a HP3DCE instrument equipped with an on-column diode array UV absorbance detector. Fused silica capillaries with an inner diameter of 50 ?m, an outer diameter of 365 ?m, and a total length of 4...
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We carried out different research projects by using our expertise in the field of the study of equilibria in solution, the synthesis and the NMR characterisation of cyclodextrin derivatives, capillary electrophoresis techniques, and electrospray mass spectrometry for the detection and the characterisation of the involved analytes. The most of our work concerns the separation science, and partic...
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This review article addresses the developments and applications of capillary electromigration methods coupled on-line with mass spectrometry for chiral analysis. The multiple enantiomeric applications of this hyphenated technology are covered including chiral analysis of drugs, food compounds, pesticides, natural metabolites, etc., in different matrices such as plasma, urine, medicines, foods, ...
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2020
ISSN: 2175-9790
DOI: 10.1590/s2175-97902019000318259